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Chemical & Engineering News: Genome Editing Writ Large

September 7, 2015

Information pouring in from accurate, low-cost gene-sequencing machines is allowing scientists to pose more and better genomic questions. But in the absence of easy-to-use genome-editing tools to experiment with, answers have been hard to come by. Starting to bridge this gap is a three-year-old editing approach called CRISPR/Cas9.

The Economist: The Age of the Red Pen

August 22, 2015

It is now easy to edit the genomes of plants, animals and humans. In the summer of 2005 Karen Aiach and her husband received heartbreaking news about their four-month-old daughter, Ornella: she had a rare disorder known as Sanfilippo syndrome.

The Vallee Foundation: Martin Jinek named a 2015 Vallee Young Investigator

August 6, 2015

Martin Jinek, PhD, Assistant Professor in the Institute of Biochemistry at the University of Zurich, has already made groundbreaking discoveries by identifying the RNA-guided endonuclease activity of Cas9 and by providing structural insights into its molecular mechanism.

WIRED: The Genesis Engine

August 1, 2015

Spiny grass and scraggly pines creep amid the arts-and-crafts buildings of the Asilomar Conference Grounds, 100 acres of dune where California's Monterey Peninsula hammerheads into the Pacific. It's a rugged landscape, designed to inspire people to contemplate their evolving place on Earth. So it was natural that 140 scientists gathered here in 1975 for an unprecedented conference. Editing the Software of Life, for Fame and Fortune

June 18, 2015

On a fall day in 2011, Jennifer Doudna was in her office at the University of California, Berkeley, chatting with one of her graduate students. She and the student, Rachel Haurwitz, had been investigating a seemingly arcane topic — how bacteria fend off invading viruses. They had homed in on a particularly interesting family of bacterial proteins, and were starting to dream a little.