Scientific Advisory Board
James Berger, Ph.D.
James is a co-founder of Caribou and a Professor in the Department of Biophysics and Biophysical Chemistry at the Johns Hopkins University School of Medicine. Prior to taking his position at Johns Hopkins in 2013, James was a Professor of Biochemistry, Biophysics and Structural Biology at the University of California, Berkeley, where he was also the director of the QB3 MacroLab and held an appointment in the Physical Biosciences Division at the Lawrence Berkeley National Laboratory. His research focuses on nucleic acid/protein interactions that are mechanistically critical to genome replication. James has won a number of awards, including the National Academy of Sciences Award in Molecular Biology and the American Chemical Society Pfizer Award in Enzyme Chemistry, and he was elected into the American Academy of Arts and Sciences in 2012. He received a B.S. in Biochemistry from the University of Utah, and a Ph.D. in Biochemistry/Structural Biology from Harvard University. He served as a Whitehead Fellow for three years at the Whitehead Institute for Biomedical Research.
Jennifer Doudna, Ph.D.
Jennifer is a co-founder of Caribou and a faculty member of the departments of Molecular and Cell Biology and Chemistry at the University of California, Berkeley, and Lawrence Berkeley National Lab, is an investigator at the Howard Hughes Medical Institute, and is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. Her research seeks to understand how non-coding RNA molecules control the expression of genetic information and she has published extensively in the field of CRISPR-Cas biology. Jennifer's work and that of her collaborator Emmanuelle Charpentier was recognized by the award of a Breakthrough Prize. Her work on CRISPR-Cas systems has also been recognized with the Paul Janssen Award for Biomedical Research and a Lurie Prize in Biomedical Sciences, and the Princess of Asturias award. Jennifer was also named to the 2015 TIME Magazine's TIME 100 list of the 100 most influential people in the world. After serving as a member of the Yale University faculty for eight years, during which time she was promoted to Henry Ford II Professor of Molecular Biophysics and Biochemistry, she joined the UC Berkeley faculty in 2002. Jennifer earned a B.A. in Biochemistry from Pomona College and a Ph.D. in Biochemistry from Harvard University.
Martin Jinek, Ph.D.
Martin is a co-founder of Caribou and an Assistant Professor at the University of Zurich in the Department of Biochemistry. His research focuses on molecular mechanisms that orchestrate cellular regulation through protein-RNA interactions. His studies include biochemical and structural approaches to investigate these processes at the atomic level. Martin has contributed significantly to the field of CRISPR biology both through basic discovery and through the invention of new CRISPR-based technologies. He has won both the Human Frontier Science Program Fellowship and the EMBO Long-term Fellowship. Martin received a B.A. in Natural Sciences and an M.S. in Chemistry from the University of Cambridge and a Ph.D. in Structural Biology from the University of Heidelberg.
Lei (Stanley) Qi, Ph.D.
Stanley is an Assistant Professor of Bioengineering at Stanford University, with a joint appointment in the Department of Chemical and Systems Biology, and a faculty fellow in ChEM-H. Stanley has pioneered the development of the CRISPR/Cas technology for targeted genome engineering in mammalian cells. His work has led to a series of gene regulation and imaging technologies, including CRISPR interference (CRISPRi), CRISPR imaging and high-throughput CRISPR screening. He also worked in the field of Synthetic Biology and developed methods to generate synthetic non-coding RNA regulators of transcription and translation, and as a molecular sensor for chemicals and intracellular proteins. Stanley obtained his Ph.D. in Bioengineering from the University of California, Berkeley, in 2012 and performed independent research as a Systems Biology Fellow in the University of California, San Francisco, from 2012 to 2014. His lab is currently applying genome engineering and CRISPR-Cas technologies for the interrogation of genetic interaction networks related to cell differentiation, proliferation, epigenetic regulation and diseases.